A review of current therapeutics targeting the mitochondrial protease ClpP in diffuse midline glioma, H3 K27-altered

- Jackson, Evangeline R., Persson, Mika L., Fish, Cameron J., Findlay, Izac J., Mueller, Sabine, Nazarian, Javad, Hulleman, Esther, van der Lugt, Jasper, Duchatel, Ryan J., Dun, Matthew D.

Current status and advances to improving drug delivery in diffuse intrinsic pontine glioma

- Arms, Lauren M., Duchatel, Ryan J., Jackson, Evangeline R., Sobrinho, Pedro Garcia, Dun, Matthew D., Hua, Susan

PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma

- Duchatel, Ryan J., Jackson, Evangeline R., Kearney, Padraic S., Jamaluddin, M. Fairuz B., Douglas, Alicia M., Beitaki, Tyrone, McEwen, Holly P., Persson, Mika L., Hocke, Emily A., Jain, Vaibhav, Aksu, Michael, Manning, Elizabeth E., Parackal, Sarah G., Murray, Heather C., Verrills, Nicole M., Hua, Susan, Cairns, Murray J., Alvaro, Frank, Dayas, Christopher V., Dun, Matthew D., Hua, S, de Bock, CE, Colino-Sanguino, Y, Kiltschewskij, Dylan, Valdes-Mora, F, Tsoli, M, Ziegler, DS, Cairns, MJ, Raabe, EH, Vitanza, NA, Hulleman, E, Phoenix, TN, Koschmann, C, Alvaro, F, Findlay, Izac J., Dayas, CV, Tinkle, CL, Wheeler, H, Whittle, JR, Eisenstat, DD, Firestein, R, Mueller, S, Valvi, S, Hansford, JR, Ashley, DM, Mannan, Abdul, Gregory, SG, Kilburn, LB, Nazarian, J, Cain, JE, Dun, MD, Staudt, Dilana E., Thomas, Bryce C., Germon, Zacary P., Laternser, Sandra

Blockade of ROS production inhibits oncogenic signaling in acute myeloid leukemia and amplifies response to precision therapies

- Germon, Zacary P., Sillar, Jonathan R., McLachlan, Tabitha, Schjenken, John E., Skerrett-Byrne, David A., Huang, Honggang, Melo-Braga, Marcella N., Plank, Maximillan W., Alvaro, Frank, Chamberlain, Janis, De Iuliis, Geoff, Aitken, R. John, Mannan, Abdul, Nixon, Brett, Wei, AH, Enjeti, Anoop K., Huang, Y, Lock, RB, Larsen, MR, Lee, Heather, Vaghjiani, V, Cain, JE, de Bock, CE, Duchatel, Ryan J., Verrills, Nicole M., Dun, Matthew D., Staudt, Dilana, Murray, Heather C., Findlay, Izac J., Jackson, Evangeline R., McEwen, Holly P., Douglas, Alicia M.

Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways

- Venneti, Sriram, Kawakibi, Abed Rahman, Ramage, Samuel, Chi, Andrew, Wen, Patrick Y., Arrillaga-Romany, Isabel, Batchelor, Tracy T., Butowski, Nicholas A., Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca A., de Groot, John, Ji, Sunjong, Mehta, M, Hall, MD, Daghistani, D, Cloughesy, TF, Ellingson, BM, Beccaria, K, Varlet, P, Kim, MM, Umemura, Y, Garton, H, Waszak, Sebastian M., Franson, A, Schwartz, J, Jain, R, Kachman, M, Baum, H, Burant, CF, Mottl, SL, Cartaxo, RT, John, V, Messinger, D, Sweha, StefanR, Qin, T, Peterson, E, Sajjakulnukit, P, Ravi, K, Waugh, A, Walling, D, Ding, Y, Xia, Z, Schwendeman, A, Hawes, D, Mota, Mateus, Yang, F, Judkins, AR, Wahl, D, Lyssiotis, CA, de la Nava, D, Alonso, MM, Eze, A, Spitzer, J, Schmidt, SV, Duchatel, Ryan J., Pun, Matthew, Dun, Matthew D., Cain, JE, Jiang, L, Stopka, SA, Baquer, G, Regan, MS, Filbin, MG, Agar, NYR, Zhao, L, Kumar-Sinha, C, Deogharkar, Akash, Mody, R, Chinnaiyan, A, Kurokawa, R, Pratt, D, Yadav, VN, Grill, J, Kline, C, Mueller, S, Resnick, A, Nazarian, J, Chung, Chan, Allen, JE, Odia, Y, Gardner, SL, Koschmann, C, Tarapore, Rohinton S.

ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma

- Jackson, Evangeline R., Duchatel, Ryan J., Le Grand, Marion, Kearney, Padraic S., Douglas, Alicia M., Findlay, Izac J., Germon, Zacary P., McEwen, Holly P., Beitaki, Tyrone S., Patabendige, Adjanie, Skerrett-Byrne, David A., Nixon, Brett, Staudt, Dilana E., Smith, Nathan D., Day, B, Manoharan, N, Nagabushan, S, Hansford, JR, Govender, D, McCowage, GB, Firestein, R, Howlett, M, Endersby, R, Persson, Mika L., Gottardo, NG, Alvaro, F, Waszak, SM, Larsen, MR, Colino-Sanguino, Y, Valdés-Mora, F, Rakotomalala, A, Meignan, S, Pasquier, E, Andre, N, Mannan, Abdul, Hulleman, E, Eisenstat, DD, Vitanza, NA, Nazarian, J, Koschmann, C, Mueller, S, Cain, JE, Dun, MD, Yadavilli, Sridevi, Parackal, Sarah, Game, Shaye, Chong, Wai Chin, Jayasekara, W. Samantha N.

B-cell Lymphoma 6 (BCL6): From Master Regulator of Humoral Immunity to Oncogenic Driver in Pediatric Cancers

- McLachlan, Tabitha, Matthews, William C., Dun, Matthew D., Jackson, Evangeline R., Staudt, Dilana E., Douglas, Alicia M., Findlay, Izac J., Persson, Mika L., Duchatel, Ryan J., Mannan, Abdul, Germon, Zacary P.

Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies

- Findlay, Izac J., De Iuliis, Geoffry N., Duchatel, Ryan J., Jackson, Evangeline R., Vitanza, Nicholas A., Cain, Jason E., Waszak, Sebastian M., Dun, Matthew D.

Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection

- Staudt, Dilana E., Murray, Heather C., Findlay, Izac J., Kearney, Padraic S., Mannan, Abdul, McEwen, Holly P., Douglas, Alicia M., Nixon, Brett, Verrills, Nicole M., Dun, Matthew D., Skerrett-Byrne, David A., Smith, Nathan D., Jamaluddin, M. Fairuz B., Kahl, Richard G. S., Duchatel, Ryan J., Germon, Zacary P., McLachlan, Tabitha, Jackson, Evangeline R.

Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma

- Duchatel, Ryan J., Mannan, Abdul, Kearney, Padraic S., Smith, Nathan D., Hindley, Kate E., Cain, Jason E., André, Nicolas, La Madrid, Andres Morales, Nixon, Brett, De Iuliis, Geoffry N., Nazarian, Javad, Irish, Kathleen, Woldu, Ameha S., Alvaro, Frank, Eisenstat, DD, Beck, A, Vitanza, NA, Mueller, S, Morris, JC, Dun, Matthew D., Hawtrey, Tom, Hindley, Phoebe A., Douglas, Alicia M., Jackson, Evangeline R., Findlay, Izac J., Germon, Zacary P., Staudt, Dilana

Can hemp help? Low-THC cannabis and non-THC cannabinoids for the treatment of cancer

- Afrin, Farjana, Chi, Mengna, Eamens, Andrew L., Duchatel, Ryan J., Douglas, Alicia M., Schneider, Jennifer, Gedye, Craig, Woldu, Ameha S., Dun, Matthew D.

Shwachman-Bodian-Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia

- Dun, Matthew D., Mannan, Abdul, Germon, Zacary, Faulkner, Sam, Chi, Mengna, Skerrett-Byrne, David, Murray, Heather C., Flanagan, Hayley, Almazi, Juhura G., Hondermarck, Hubert, Nixon, Brett, De Iuliis, Geoff, Rigby, Callum J., Chamberlain, J, Alvaro, F, de Bock, CE, Morris, JC, Enjeti, Anoop K., Verrills, Nicole M., Butler, Stephen, Toop, Hamish D., Beck, Dominik, Connerty, Patrick, Sillar, Jonathan, Kahl, Richard G. S., Duchatel, Ryan J.

Reduced cortical somatostatin gene expression in a rat model of maternal immune activation

- Duchatel, Ryan J., Harms, Lauren R., Meehan, Crystal L., Michie, Patricia T., Bigland, Mark J., Smith, Doug W., Jobling, Phillip, Hodgson, Deborah M., Tooney, Paul A.

Signal transduction in diffuse intrinsic pontine glioma

- Duchatel, Ryan J., Jackson, Evangeline R., Alvaro, Frank, Nixon, Brett, Hondermarck, Hubert, Dun, Matthew D.

White matter neuron biology and neuropathology in schizophrenia

- Duchatel, Ryan J., Shannon Weickert, Cynthia, Tooney, Paul A.

Effects of maternal immune activation on adult brain neurobiology

- Duchatel, Ryan J.

Late gestation immune activation increases IBA1-positive immunoreactivity levels in the corpus callosum of adult rat offspring

- Duchatel, Ryan J., Meehan, Crystal L., Harms, Lauren R., Michie, Patricia T., Bigland, Mark J., Smith, Doug W., Walker, Frederick R., Jobling, Phillip, Hodgson, Deborah M., Tooney, Paul A.

Increased white matter neuron density in a rat model of maternal immune activation - implications for schizophrenia

- Duchatel, Ryan J., Jobling, Phillip, Graham, Brett A., Harms, Lauren R., Michie, Patricia T., Hodgson, Deborah M., Tooney, Paul A.